COMPLIMENTARY CLEANSING KIT WITH EVERY ORDER OF MELTING BALM*. SHOP NOW.

COMPLIMENTARY CLEANSING KIT WITH EVERY ORDER OF MELTING BALM*. SHOP NOW.

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SEXUAL WELLNESS

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Before and Afters

The Science

About

Reviews

Sustainability

Clinically formulated and scientifically vetted products that perform at the highest cellular level with precision and potency. Our IMBIBE gold-standard means we leave out fillers, additives, bulking agents and any other questionable ingredients, whilst including clinical level actives from our hand selected ingredients.

We create formulations hand picked for their potency, precision and clean standard.

Clean Formulations with Clinical Level Actives


At the core of our mission lies the desire to make every day more beautiful, more radiant, and more vital for you.

This is a new era where potency transcends product offerings; with clinical-level actives in 100% clean formulations. We never rush products out to you to ride the latest trends. The range is subject to a deliberate and meticulous process, where time and great care are taken to curate high-performance products. Our products typically take 2 or more years to create for you with hundreds of rounds of testing for efficacy.


This is an era where our products are scientifically validated for effectiveness. An era where you matter and your results matter more than anything else. We’re just not interested in product for the sake of product - every formulation has its own place in your wellness routine.


Each product is specifically designed to fulfil your specific needs.


Welcome to the next generation of Ingestible Beauty.


We call it Science Meets Beauty.

OUR PROMISE TO YOU

OUR PROMISE TO YOU

We’re not interested in mediocre, there’s enough of that.

We pair the finest ingredients with the most cutting-edge technology to bring you a range that is unparalleled.

What truly sets us apart is our unwavering focus on results, uncompromised health, and the radiant glow that can only be achieved through deeply nourished, thriving skin.

DISCOVER THE RADICAL TRANSFORMATIONS FROM OUR COMMUNITY.

We’re not interested in mediocre, there’s enough of that.

We pair the finest ingredients with the most cutting-edge technology to bring you a range that is unparalleled.

What truly sets us apart is our unwavering focus on results, uncompromised health, and the radiant glow that can only be achieved through deeply nourished, thriving skin.

DISCOVER THE RADICAL TRANSFORMATIONS FROM OUR COMMUNITY.


MORE BEFORE AND AFTERS

100% CLEAN, 100% PERFORMANCE DRIVEN

100% CLEAN, 100% PERFORMANCE DRIVEN

Being meticulous about each ingredient, benefit and resource has allowed us to create our results driven, clinically-driven Ingestible Beauty and Skin Science ranges with a holistic focus on natural ingredients, sustainable sourcing and skin and gut nutrition.

There are no fillers, no binding ingredients, no artificial flavours, fragrances, synthetics, parabens, or ingredients anywhere in our range - ever. This is the heart-beat of our business.

Being meticulous about each ingredient, benefit and resource has allowed us to create our results driven, clinically-driven Ingestible Beauty and Skin Science ranges with a holistic focus on natural ingredients, sustainable sourcing and skin and gut nutrition.

There are no fillers, no binding ingredients, no artificial flavours, fragrances, synthetics, parabens, or ingredients anywhere in our range - ever. This is the heart-beat of our business.

CLEAN INGREDIENTS. EXCEPTIONAL RESULTS.

CLEAN INGREDIENTS. EXCEPTIONAL RESULTS.

Explore the curated ingredients used across our high-performance range.

Explore the curated ingredients used across our high-performance range.

WHY IT WORKS

WHY IT WORKS

Our formulations are meticulously crafted with precision and care, ensuring quality over quantity, every single time.

Our formulations are meticulously crafted with precision and care, ensuring quality over quantity, every single time.

SCIENTIFIC REFERENCES

SCIENTIFIC REFERENCES

+CALM/SLEEP
Magnesium (Mg)

Observational studies suggested an association between higher Mg intake and daytime falling asleep, sleepiness, snoring, and sleep duration in healthy adults. Positive effect of magnesium supplementation on The Pittsburgh Sleep Quality Index (PSQI) score, sleep efficiency, and sleep time. Arab, A., Rafie, N., Amani, R. and Shirani, F., 2023. The role of magnesium in sleep health: a systematic review of available literature. Biological Trace Element Research, 201(1), pp.121-128. Ref.

Higher Mg intake is associated with normal hours of sleep, and low level of consumption is linked to both shorter and longer sleep. Grandner, M.A., Jackson, N., Gerstner, J.R. and Knutson, K.L. (2013) 'Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample', Appetite, 64, pp. 71-80. Ref

Biological clock and magnesium status are linked. Studies have found that people deficient in magnesium also have decreased melatonin, a hormone that maintains the circadian rhythm. The circadian rhythm causes changes in the body according to the day-night cycle, such as feelings of sleepiness and wakefulness. Feeney, K., Hansen, L., Putker, M. et al. (2016) 'Daily magnesium fluxes regulate cellular timekeeping and energy balance', Nature, 532, pp. 375-379. Ref

Durlach, J., Bac, P., Bara, M. and Guiet-Bara, A., 2002. Biorhythms and possible central regulation of magnesium status, phototherapy, darkness therapy and chronopathological forms of magnesium depletion. Magnesium research, 15(1-2), pp.49-66. Ref

Supplementation of magnesium appears to improve subjective measures of insomnia such as insomnia severity index (ISI) score, sleep efficiency, sleep time and sleep onset latency, early morning awakening, and likewise, insomnia objective measures such as concentration of serum renin, melatonin, and serum cortisol, in elderly people. Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M.M., Hedayati, M. and Rashidkhani, B., 2012. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences, 17(12), p.1161. Ref.


Ashwagandha Root Withania Somnifera

Ashwagandha (21g of standardised withanolide for 6 weeks) improved the quality of sleep, and reduced non-restorative sleep measures in healthy subjects with frequent non-restorative sleep. Deshpande, A., Irani, N., Balkrishnan, R. and Benny, I.R. (2020) 'A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults', Sleep Med, 72, pp. 28-36. Ref

Ashwagandha has been shown to have beneficial effects in decreasing time to fallasleep, improving duration, quality of sleep, and mood upon awakening. (literature review) Ashraf, S., Shah, K., Aedma, K., Mansuri, Z. and Jain, S. (2022) 'Safety and Efficacy of Ashwagandha for sleep: A Systematic Review', Sleep, 45(Supplement_1), pp. A305. Ref

Ashwagandha extract appears to has a beneficial effect in improving sleep in adults. (literature review) Cheah, K.L., Norhayati, M.N., Husniati Yaacob, L. and Abdul Rahman, R. (2021) 'Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis', PLoS ONE, 16(9), e0257781. Ref

Ashwagandha root extract can improve sleep quality and can help in managing insomnia. Ref


Beta vulgaris L.

Numerous studies show that beetroots contain large amounts of valuable vitamins and minerals, as well as antioxidants, especially potassium, magnesium, iron, vitamins A, C, and B6. Beetroots greatly improve blood circulation, including in our brains, and the compounds in the beetroot are extremely helpful in maintaining the health of the nervous system. By consuming beetroots regularly, the risk of various types of dementia, such as Alzheimer’s can be reduced, and keep the memory sharp. In addition to improving its blood circulation, it also contains substances that, when transformed in our body, also lower blood pressure. Székely, D., & Máté, M. (2022). Red Beetroot (Beta Vulgaris L.). In P. Kaushik (Ed.), *Advances in Root Vegetables Research*. IntechOpen. DOI: 10.5772/intechopen.106692. Ref

Beetroot is a good source of dietary fiber, which supports digestive health by promoting regular bowel movements, preventing constipation, and supporting a healthy gut microbiota. Fiber-rich foods like beetroot are essential for maintaining gastrointestinal function.  Slavin, J. L. (2013). Dietary fiber and body weight. Nutrition, 29(1), 10-19. Ref

Nitric oxide produced from dietary nitrates in beetroot has been associated with improved cognitive function and blood flow to the brain. Regular consumption may help maintain cognitive health and reduce the risk of age-related cognitive decline. Presley, T.D., Morgan, A.R., Bechtold, E., Clodfelter, W., Dove, R.W., Jennings, J.M., Kraft, R.A., King, S.B., Laurienti, P.J., Rejeski, W.J. and Burdette, J.H., 2011. Acute effect of a high nitrate diet on brain perfusion in older adults. Nitric Oxide, 24(1), pp.34-42. Ref

Betalains fount in beetroowork as as antioxidant and anti-inflammatory agents play an important role in the release of NO and decrease of blood pressure. Modulation of oxidative and inflammatory factors may also attribute to regulatory function in metabolic syndrome such as blood pressure lowering effect and more importantly in reducing hyperlipidemia. In addition to betalanin, flavonoids and fibers in red beetroots attributed to the blood glucose lowering effect. Hadipour, E., Taleghani, A., Tayarani‐Najaran, N. and Tayarani‐Najaran, Z., 2020. Biological effects of red beetroot and betalains: A review. Phytotherapy research, 34(8), pp.1847-1867. Ref


L-Theanine

L-THE supplementation can assist in reducing acute stress and anxiety in people experiencing stressful situations. Everett, J.M., Gunathilake, D., Dufficy, L., Roach, P., Thomas, J., Upton, D. and Naumovski, N. (2016) 'Theanine consumption, stress and anxiety in human clinical trials: A systematic review', J Nutr Intermed Metab, 4, pp. 41-42. Ref

200 mg/day before sleep for 4 weeks: Stress-related symptom (i.e., depression, anxiety-trait, and sleep) scores decreased and cognitive function (i.e., verbal fluency and executive function) scores improved after four weeks of L-theanine administration. The reduction in sleep quality problems (disturbances in sleep latency, sleep disturbance, and use of sleep medication) was greater in the L-theanine administration compared to the placebo administration, while verbal fluency, especially letter fluency, was improved in the L-theanine administration among individuals who showed relatively low performance at pretreatment. Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M. and Kunugi, H. (2019) 'Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: A randomized controlled trial', Nutrients, 11(10), 2362. Ref

200 mg of l-Theanine (Suntheanine, Taiyo Kagaku Inc., Japan) dissolved in 100 ml of water was used as a treatment. l-Theanine exerts anti-stress effects during an acute stress challenge. Kimura, K., Ozeki, M., Juneja, L.R. and Ohira, H. (2007) 'L-Theanine reduces psychological and physiological stress responses', Biol Psychol, 74(1), pp. 39-45. Ref

May help to increase alpha brain wave activity, associated with a state of wakeful relaxation and mental alertness. Nobre, A.C., Rao, A. and Owen, G.N. (2008) 'L-theanine, a natural constituent in tea, and its effect on mental state', Asia Pac J Clin Nutr, 17(Suppl 1), pp. 167-168. Ref

Theanine intake suppressed initial stress response. Unno, K., Tanida, N., Ishii, N., Yamamoto, H., Iguchi, K., Hoshino, M., Takeda, A., Ozawa, H., Ohkubo, T., Juneja, L.R. and Yamada, H. (2013) 'Anti-stress effect of theanine on students during pharmacy practice: Positive correlation among salivary α-amylase activity, trait anxiety and subjective stress', Pharmacol Biochem Behav, 111, pp. 128-135. Ref


Passionflower Extract Passiflora Incarnata (5:1 extract)

Consumption of low dose of Passiflora incarnata, yields short-term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality. Ngan, A. and Conduit, R., 2011. A double‐blind, placebo‐controlled investigation of the effects of Passiflora incarnata (Passionflower) herbal tea on subjective sleep quality. Phytotherapy Research, 25(8), pp.1153-1159. Ref

Passiflora extract is an effective drug for the management of generalised anxiety disorder. Akhondzadeh, S., Naghavi, H.R., Vazirian, M., Shayeganpour, A., Rashidi, H. and Khani, M., 2001. Passionflower in the treatment of generalized anxiety: A pilot double‐blind randomized controlled trial with oxazepam. Journal of clinical pharmacy and therapeutics, 26(5), pp.363-367. Ref

Passiflora incarnata has demonstrated anxiolytic effects, aiding in the reduction of anxiety symptoms. It interacts with gamma-aminobutyric acid (GABA) receptors, promoting relaxation and calmness. Appel, K., Rose, T., Fiebich, B., Kammler, T., Hoffmann, C. and Weiss, G., 2011. Modulation of the γ‐aminobutyric acid (GABA) system by Passiflora incarnata L. Phytotherapy Research, 25(6), pp.838-843. Ref

Research suggests that Passiflora incarnata can enhance sleep quality by regulating neurotransmitters involved in sleep-wake cycles, leading to deeper and more restful sleep. Miyasaka, L.S., Atallah, Á.N. and Soares, B., 2007. Passiflora for anxiety disorder. Cochrane Database of Systematic Reviews, (1). Ref

Passiflora incarnata exhibits mild sedative properties, which can help in inducing relaxation and easing nervous tension without causing significant sedation or impairment. Aslanargun, P., Cuvas, O., Dikmen, B., Aslan, E. and Yuksel, M.U., 2012. Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia. Journal of anesthesia, 26, pp.39-44. Ref

+COLLAGEN

Carolyn Ann Sarbacher and Jaroslava T. Halper, Connective Tissue and Age-Related Diseases, Biochemistry and Cell Biology of Ageing: Part II Clinical Science, 10.1007/978-981-13-3681-2_11, (281-310), (2019). Ref

Carlos A. López‐Morales, Said Vázquez‐Leyva, Luis Vallejo‐Castillo, Gregorio Carballo‐Uicab, Leslie Muñoz‐García, José Enrique Herbert‐Pucheta, L. Gerardo Zepeda‐Vallejo, Marco Velasco‐Velázquez, Lenin Pavón, Sonia M. Pérez‐Tapia and Emilio Medina‐Rivero, Determination of Peptide Profile Consistency and Safety of Collagen Hydrolysates as Quality Attributes, Journal of Food Science, 84, 3, (430-439), (2019). Wiley Online Library

Rachael Zoe Murray, Zoe Elizabeth West, Allison June Cowin and Brooke Louise Farrugia, Development and use of biomaterials as wound healing therapies, Burns & Trauma, 10.1186/s41038-018-0139-7, 7, 1, (2019). Ref

Bor-Shuang Liaw, Fangyu Xing, Dan Wang, Fei Gao, Jingsong Lu, Jing Yu, Xiaodan Sun, Xiumei Wang, Qingling Feng, Guifeng Zhang and Lingyun Zhao, Effect of in vitro Collagen Fibrillogenesis on Langmuir-Blodgett (LB) Deposition for Cellular Behavior Regulation, Colloids and Surfaces B: Biointerfaces, 10.1016/j.colsurfb.2019.03.053, (2019). Ref

Suman Sinha-Ray, Bio-Waste Based Nanofiber Materials, Reference Module in Materials Science and Materials Engineering, 10.1016/B978-0-12-803581-8.11548-6, (2019). Ref

John.A.M. Ramshaw, Jerome A. Werkmeister and Veronica Glattauer, Recent progress with recombinant collagens produced in Escherichia coli, Current Opinion in Biomedical Engineering, 10.1016/j.cobme.2019.06.001, (2019). Ref

 Yingyue Chen, Huoxi Jin, Fei Yang, Shujie Jin, Chenjuan Liu, Liukai Zhang, Ju Huang, Shiguang Wang, Zhongyong Yan, Xuwei Cai, Rui Zhao, Fangmiao Yu, Zuisu Yang, Guofang Ding and Yunping Tang, Physicochemical, antioxidant properties of giant croaker (Nibea japonica) swim bladders collagen and wound healing evaluation, International Journal of Biological Macromolecules, 10.1016/j.ijbiomac.2019.07.111, (2019). Ref

Caterina Tricase, Vera Amicarelli, Emilia Lamonaca and Roberto Leonardo Rana, Economic Analysis of the Barley Market and Related Uses, Grasses as Food and Feed, 10.5772/intechopen.78967, (2018). Ref

Hau Van Duong, Trang The Lieu Chau, Nhan Thi Thanh Dang, Duc Van Nguyen, Son Lam Le, Thang Sy Ho, Tuyen Phi Vu, Thi Thi Van Tran and Thanh-Dinh Nguyen, Self-aggregation of water-dispersible nanocollagen helices, Biomaterials Science, 6, 3, (651), (2018). Cef

Hermann Ehrlich, Marcin Wysokowski, Sonia Żółtowska-Aksamitowska, Iaroslav Petrenko and Teofil Jesionowski, Collagens of Poriferan Origin, Marine Drugs, 16, 3, (79), (2018). Ref

Takeshi ISHINO, Mayuko HASHIMOTO, Misato AMAGASA, Natsuko SAITO, Osamu DOCHI, Rikio KIRISAWA and Hiroshi KITAMURA, Establishment of protocol for preparation of gene-edited bovine ear-derived fibroblasts for somatic cell nuclear transplantation , Biomedical Research, 10.2220/biomedres.39.95, 39, 2, (95-104), (2018). Ref

Sakthivel Nagarajan, Socrates Radhakrishnan, S. Narayana Kalkura, Sebastien Balme, Philippe Miele and Mikhael Bechelany, Overview of Protein‐Based Biopolymers for Biomedical Application, Macromolecular Chemistry and Physics, 1900126, (2019). Wiley Online Library

David Vollmer, Virginia West and Edwin Lephart, Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome, International Journal of Molecular Sciences, 10.3390/ijms19103059, 19, 10, (3059), (2018). Ref

Changwoo Nam, Jongsun Yoon, Sang A Ryu, Chang-Hyung Choi and Hyomin Lee, Water and Oil Insoluble PEGDA-Based Microcapsule: Biocompatible and Multicomponent Encapsulation, ACS Applied Materials & Interfaces, 10.1021/acsami.8b16876, (2018). Ref

Xinhui Lin, Yinyue Chen, Huoxi Jin, Qiaoling Zhao, Chenjuan Liu, Renwei Li, Fangmiao Yu, Yan Chen, Fangfang Huang, Zuisu Yang, Guofang Ding and Yunping Tang, Collagen Extracted from Bigeye Tuna (Thunnus obesus) Skin by Isoelectric Precipitation: Physicochemical Properties, Proliferation, and Migration Activities, Marine Drugs, 10.3390/md17050261, 17, 5, (261), (2019). Ref

Hyunwoo Moon, Seunghwan Choy, Yeonju Park, Young Mee Jung, Jun Mo Koo and Dong Soo Hwang, Different Molecular Interaction between Collagen and α- or β-Chitin in Mechanically Improved Electrospun Composite, Marine Drugs, 10.3390/md17060318, 17, 6, (318), (2019). Ref

Kenji Sugibayashi, Eddy Yusuf, Hiroaki Todo, Sabrina Dahlizar, Pajaree Sakdiset, Florencio Jr Arce and Gerard Lee See, Halal Cosmetics: A Review on Ingredients, Production, and Testing Methods, Cosmetics, 10.3390/cosmetics6030037, 6, 3, (37), (2019). Ref

Haseeb Ahsan, Immunopharmacology and immunopathology of peptides and proteins in personal products, Journal of Immunoassay and Immunochemistry, 10.1080/15321819.2019.1629590, (1-9), (2019). Ref

Sajee Thaweekitphathanaphakdee, Pithi Chanvorachote, Sagaw Prateepchinda, Mattaka Khongkow and Apirada Sucontphunt, Abalone Collagen Extracts Potentiate Stem Cell Properties of Human Epidermal Keratinocytes, Marine Drugs, 10.3390/md17070424, 17, 7, (424), (2019). Ref

    Zague, V 2008 “ A new view concerning the effects of collagen hydrolysate intake on skin properties”, Archives of Dermatological Research,Springer Link, Ref

    Pyun, HB, Kim, M, Park, J, Sakai, Y, Numata, N, Shin, J, Shin, H, Kim, D, Hwang, J 2012 “Effects of Collagen Tripeptide Supplement on Photoaging and Epidermal Skin Barrier in UVB-exposed Hairless Mice”, Preventive Nutrition and Food Science,National Institutes of Health, Ref

    Choi,S, Lee, Y, Kim, B, Shin, H, Seo, D, Lee, S, Kim, B 2014 “Effects of collagen tripeptide supplement on skin properties: A prospective, randomized, controlled study”, Journal of Cosmetic and Laser Therapy,Taylor and Francis Online, Ref

    Zague, V, Freitas, V, Rose, M, Castro, G, Jaeger, R, Machado-Santelli, G 2011 “ Collagen Hydrolysate Intake Increases Skin Collagen Expression and Suppresses Matrix Metalloproteinase 2 Activity”, Journal of Medicinal Food,Mary Ann Liebert Publishers, Ref

    Tanaka, M, Koyama, Y, Nomura, Y 2009 “ Effects of Collagen Peptide Ingestion on UV-B-Induced Skin Damage”, Bioscience, Biotechnology, and Biochemistry,Taylor and Francis Online, Ref

    Borumand, M, Sibilla, S 2015 “Effects of a nutritional supplement containing collagen peptides on skin elasticity, hydration and wrinkles”, Journal of Medical Nutrition & Nutraceuticals, Ref

    Sibilla, S, Godfrey, M, Brewer, S, Budh-Raja, A, Genovese, L 2015 “An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies”, The Open Nutraceuticals Journal,Benthan Open, Ref

    Gómez-Guillén, M, Giménez, B, López-Caballero, M, Montero, M 2011 “Functional and bioactive properties of collagen and gelatin from alternative sources: A review”, Food Hydrocolloids,Science Direct, Ref

    Li, G, Fukunaga, S, Takdenouchi, K, Nakamura, F 2005 “Comparative study of the physiological properties of collagen, gelatin and collagen hydrolysate as cosmetic materials”, International Journal of Cosmetic Science,Wiley Online Library, Ref

    Dybka, K, Walczak, P 2009 “Collagan hydrolysates as a new diet supplement”, Cyrena, Ref

    Ohara, H, Ichikawa, S, Matsumoto, H, Akiyama, M, Fujimoto, N, Kobayashi, T, Tajima, S 2010 “Collagen-dervied dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts”, Journal of Dermatology,Wiley Online Library, Crossref

    Song, H, Li, B 2017 “Beneficial Effects of Collagen Hydrolysate: A Review on Recent Developments”, Advanced Innovation Center for Food Nutrition and Human Health,Biomedical Journal of Scientific and Technical Research, Ref

    Liu, D Nikoo, M, Boran, G, Zhou, P, Regenstein, J 2016 “Collagen and Gelatin”, Annual Review of Food Science and Technology,Annual Reviews, Crossref

    Wang, L, Wang, Q, Qian, J, Liang, Q, Wang, Z, Xu, J, He, S, Ma, A 2015 “Bioavailability and Bioavailable Forms of Collagen after Oral Administration to Rats”, Journal of Agricultural and Food Chemistry,ACS Publications, Ref

    Koyama, Y 2016 “Effects of Collagen Ingestion and their Biological Significance”, Research Institute of Biomatrix,Journal of Nutrition and Food Sciences, Ref

    Kantor, I et al. 2002. Results of a Study Evaluating the Use of a Dietary Supplement Formula in the Management of Age-Related Skin Changes in Women with Moderate to Severe Wrinkling of the Periorbital Area. Journal of the American Nutraceutical Association. Vol 5, No.2.

    SOUKEN study 2008, Tokyo Japan: two month study hydrolyzed collagen.

    DERMSCAN study, 2008, Lyon France. Cutaneous properties of hydrolyzed collagen.

    Tanaka et al. Effects of collagen peptide ingestion on UV-B-induced skin damage. Biosci Biotechnol Biochem 73:930-932 (2009).

    Matsuda, N.; Koyama, Y., Hosaka, Y., Ueda, H., Watanabe, T., Araya, T., Irie, S. and Takehana K. (2006). “Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis”. Journal of nutrition vitaminology 52: 211-215.

    Sumada E, Hirota A et al.: The effect of oral ingest of collagen peptide on skin hydration and biochemical data on blood. J. Nutri Food 7, (2004) 1-8

    Morganti P, Randazzo S, Bruno C: Oral treatment of skin dryness. Cosmet Toilet. 103 (1988) 77-80

    Koyama. Effects of collagen peptide ingestion on the skin. Shokuhin-To-Kaihatsu 44:10-12 (2009) (in Japanese).

    Rousselot Publication, 2009. Hydrolyzed Collagen and Skin Health 2009 clinical studies results.

    Eskelinin, A. and Santalahti, J. (1992) Special Natural cartilage polysaccharides for the treatment of sun-damaged skin in females. J Int Med Res; 20(2): 99 – 105

    Proksch et al. (2014) Oral Supplementation of Specific Collagen Peptides Has beneficial Effects on Human Skin Physiology: A Double Blind, Placebo-Controlled Study. Skin Pharmacol Physiol 2014; 27:47:47 – 55

    Zague et al. (2011) Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. Journal of Medicinal Food 14 (6) 2011, 618–624

    Matsumoto, H. et al. (2006) Clinical effect of fish type I collagen hydrolysate on skin properties. ITE Lett. 7. 386 – 390

    Ohara H et al. (2010) Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. The Journal of Dermatology Volume 37, Issue 4, pages 330–338.

    Clark KL et al. (2008) 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current Medical Research and Opinion Vol. 24, No. 5, 2008, 1485–1496

    Benito-Ruiz P et al. (2009) Randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. Int J Food Sci Nutr; 60 Suppl 2:99-113.

    Zdzieblik, D., Oesser, S., Baumstark, M. W., Gollhofer, A., & König, D. (2015). Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial. British Journal of Nutrition, 114(08), 1237-1245.

    Hays, N. P., Kim, H., Wells, A. M., Kajkenova, O., & Evans, W. J. (2009). [Effects of whey and fortified collagen hydrolysate protein supplements on nitrogen balance and body composition in older women (www.ncbi.nlm.nih.gov/pubmed/19465192). Journal of the American Dietetic Association, 109(6), 1082-1087.

    The Collagen Family, Ref 

    Collagen: The Fibrous Proteins of the Matrix, Ref

    Collagen alterations in chronically sun-damaged human skin. Ref

    Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue. Ref

    Smoking affects collagen synthesis and extracellular matrix turnover in human skin. Ref

    Oral Collagen Supplementation: A Systematic Review of Dermatological Applications Ref

    Decreased Collagen Production in Chronologically Aged Skin. Ref

    What is collagen? Ref

    Collagen accounts for around 25% of total protein content in the body. Because of this, regularly consuming bioactive collagen peptides has been shown to be beneficial for our health. Collagen improves muscle strength and promotes healthy fat loss (PMID: 31010031).

    Collagen increases bone mineral density in those with osteoporosis and osteopenia (PMID: 34520654).

    Collagen reduces joint pain (PMID: 33562729).

    Collagen grows and smooths nails (PMID: 28786550).

    Collagen improves facial skin moisture, elasticity and wrinkles (PMID: 26840887)

    Verisol® Review of Literature:

    Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study. The study suggests that oral intake of specific collagen hydrolysate can significantly improve skin elasticity and potentially provide moisturizing effects, particularly in older women. Ref.

    Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis. Overall, the study suggests that the oral consumption of VERISOL® collagen peptides can be effective in reducing skin wrinkles and stimulating the synthesis of key components of the dermal matrix, supporting its potential use in addressing skin ageing. Ref

    Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails. Overall, the study suggests that specific bioactive collagen peptides may be effective in improving nail growth rate, strengthening nails, and alleviating symptoms of brittle nails. Ref

    Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. Overall, the study highlights the potential of bioactive collagen peptides in improving cellulite appearance and skin health particularly in women of normal body weight, by positively influencing dermal connective tissue synthesis. Ref

    Oesser, S. (2020). The oral intake of specific Bioactive Collagen Peptides has a positive effect on hair thickness. Overall, the study suggests that supplementation with specific BCP can lead to increased hair thickness and improved hair metabolism in women, highlighting the potential benefits of BCP for hair health. 

    +VEGAN COLLAGEN


    Tremella fuciformis
    Medicinal value of the genus Tremella pers. (Heterobasidiomycetes). Ref

    Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging. Ref

    Skin Wound Healing Promoting Effect of Polysaccharides Extracts from Tremella fuciformis and Auricularia auricula on the ex-vivo Porcine Skin Wound Healing Model. Ref

    Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. Ref

    Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review. Ref

    he optimum submerged culture condition of the culinary-medicinal white jelly mushroom Tremella fuciformis (tremellomycetes) and its antioxidant properties. Ref


    Rice Bran Solubles
    Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study. Ref

    Dietary tocotrienol and UVB-induced skin damage. Ref


    L-Glycine
    Oxidative stress, aging, and diseases. Clinical interventions in ageing. Liguori I, R. G.-M. (2018, April). Oxidative stress, aging, and diseases. Clinical interventions in ageing, 13, 757-772.  Ref

    L-Glycine: a novel antiinflammatory, immunomodulatory. Zhong, Z., Wheeler, M. D., Li, X., Froh, M., Schemmer, P., Yin, M., . . . Lemasters, J. J. (2003, March). L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Current opinion in clinical nutrition and metabolic care, 6(2), 229–240. Ref


    L-Lysine HCl
    Spotlight on Supplements: L-Lysine. Ref.

    +GUT HEALTH, PROBIOTICS AND SKIN HEALTH

    Salem, I, Ramser, A, Isham, N, Ghannoum, M 2018 “The Gut Microbiome as a Major Regulator of the Gut-Skin Axis”, US National Library of Medicine, Natioanl Institutes of Health Ref

    Grice, E, Serge, J 2013 “The Skin Microbiome”, US National Library of Medicine, National Institute of Health Ref

     

    Chen, Y, Fischbach, M, Belkaid, Y 2018 “ Skin microbiota-host interactions”, US National Library of Medicine, National Institutes of Health Ref

    Byrd, A, Belkaid, Y, Serge, J 2018 “ The human skin microbiome”, Natures Reviews, Microbiology Ref

    Vaughn, A, Notay, M, Clark, A, Sivamani, R 2017 “Skin-gutaxis: The relationship between intestinal bacteria and skin health”, World Journal of Dermatology, Baishideng Publishing Group Inc Ref


    Sivamani, R 2018 “The Gut-Skin Axis and Mechanisms for Communication”, Natural Medicine Journal Ref

    Roudsari, MR, Karimi, R, Sohrabvandi, S, Mortazavian, AM 2015 “Health effects of probiotics on the skin”, US National Library of Medicine,National Institutes of Health, Ref

    Stoller-Conrad, J 2015 “Microbes Help Produce Serotonin in Gut” California Institute of Technology,Caltech, Ref

    Rowland, I, Gibson, G, Heinken, A, Scott, K, Swann, J, Thiele, I, Tuohy, K 2018 “Gut microbiota functions: metabolism of nutrients and other food components”, US National Library of Medicine,National Institutes of Health, Ref

    Picjard, JM, Zeng MY, Caruso, R, Núñez, G 2017 “Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease”, US National Library of Medicine,National Institutes of Health, Ref

    Harvard School of Public Health The Nutrition Source: The Microbiome, Ref

    Mabbott, NA 2015 “A breakdown in communication? Understanding the effects of aging on the human small intestine epithelium”, US National Library of Medicine,National Institutes of Health, Ref

    Shi, LH, Balakrishnan, K, Thiagarajah, K, Ismail, NIM, Yin, OS 2016 “Beneficial Properties of Probiotic”, Tropical Life Science Research,National Institutes of Health, Ref

    Ghazzewi FH, Tester, RF 2014 “Impact of prebiotics and probiotic on skin health”, Wageningen Academic Publishers,Ref

    Levkovich T, Poutahidis, T, Smilie, C, Varian, B, Ibrahim, Y, Lakritz, J, Alm, E, Erdman, S 2013 “Probiotic Bacteria Induce a ‘Glow of Health’, Plos One Journals,Ref

    Chapat, L, Chemin, K, Dubois, B, Bourdet-Sicard, R, Kaiserlian, D 2004 “Lactobacilluscaseireduces CD8+T cell-mediated skin inflammation”, European Journal of Immunology,Wiley Online Library, Ref

    Lew, LC, Liong, MT 2013 “Bioactive from probiotics for dermal health: functions and benefits”, Journal of Applied Microbiology,Wiley Online Library, https://onlinelibrary.wiley.com/doi/full/10.1111/jam.12137

    Shu, M, Wang, Y, Yu, J, Kuo, S, Coda, A, Jiang, Y, Gallo, R, Huang, C 2013 “ Fermentation of Propionibacterium acnes,a Commensal Bacterium in the Human Skin Microbiome, as Skin Probiotics against Methicillian-Resistant Staphylococcus aureus, Plos One,Ref

    Arck, P, Handjiski, B, Hagen, E, Pincus, M, Bruenahl, C, Bienenstock, J, Paus, R 2010 “Is there a ‘gut-brain-skin axis?”, Experimental Dermatology,Wiley Online Library, Ref

    Miyazaki, K, Masuoka, N, Kano, M, Lizuka, R 2013 “Bifidobacteriumfermented milk and galacto-oligosaccharides lead to improved skin health by decreasing phenols production by gut microbiota”, Wageningen Academic Publishers,Ref

    Wong, V, Martindale, R, Longaker, M, Gurtner, G 2013 “From Germ Theory to germ Therapy: Skin Microbiota, Chronic Wounds, and Probiotics”, Plastic and Reconstructive Surgery,Journal of the American Society of Plastic Surgeons, Ref

    Guéniche, A, Bastien, p, Ovigne, J, Kermici, M, Courchay, G, Chevalier,V, Breton, L, Castiel-Higounenc, I 2010 “ Bifidobacterium longumlysate, a new ingredient for reactive skin”, Experimental Dermatology,Wiley Online Library, Ref

    Bouilly-Gauthier, D, Jeannes, C, Maubert, Y, Duteil, L, Queille-Roussel, C, Piccardi, N, Montastier, C, Manissier, P, Piérard, G, Ortonne, JP 2010 “Clinical evidence of benefits of a dietary supplement containing probiotic and carotenoids on ultraviolet-induced skin damage”, British Journal of Dermatology,Wiley Online Library, Ref

    Isolauri, E, Arvola, T, Sütas, Y, Moilanen, E, Salminen, S 2008 “Probiotics in the management of atopic eczema”, Clinical and amo: Experimental Allergy,Wiley Online Library, Ref

    Roudsari, MR, Karimi, R, Sohrabvandi, S, Mortazavian, AM 2015 “Health Effects of Probiotics on the Skin”, Critical Reviews in Food Science and Nutrition,Taylor and Francis Online, Ref

    Maguire, M, Maguire, G 2017 “The role of microbiota, and probiotics and prebiotics in skin health”, Archives of Dermatological Research,Springer Link, https://link.springer.com/article/10.1007/s00403-017-1750-3

    Daliri, E, Lee, B 2015 “New perspectives on probiotics in health and disease”, Food Science and Human Wellness,Science Direct, Ref

    Bowe, W, Logan, A 2011 “Acne vulgaris, probiotics and the gut-brain-skin axis – back to the future?”, Gut Pathogens,BMC Part of Springer Nature, Ref

    Grice, E 2014 “The skin microbiome: potential for novel diagnostic and therapeutic approaches to cutaneous disease”, Semin Cutan Med Surg,HHS Public Access, Ref

    Krutmann, J, Pre-and probiotics for human skin”, Journal od Dermatology Science”,Elsevier, Ref

    Simmering, R, Breves, R 2009 “Pre- and probiotic cosmetics”, European PMC,Ref

    Schagen, S, Zampeli, V, Makrantonaki, E, Zouboulis, C 2012 “Discovering the link between nutrition and skin aging”, Dermato-Endocrinology,Taylor and Franics Online, Ref

    Mori, N, Kano, M, Masuoka, N, Konno, T, Suzuki, Y, Miyazaki, M, Ueki, Y 2015 “Effect of probiotic and prebiotic fermented milk on skin and intestinal conditions in health young female students”, Bioscience of Microbiota, Food and Health,Jstage, Ref

    O’Neill, C, Monteleone, G, McLaughlin, J, Paus, R 2016 “The gut-skin axis in health and disease: A paradigm with therapeutic implications”, BioEssays,Wiley Online Library, Ref

    Fucha-Tarlovsky, V, Marquez-Barba, M, Sriram, K 2016 “Probiotics in dermatologic practice”, Nutrition,Elsevier, Science Direct, Ref

    Viljanen, M, Savilahity, E, Haahtela, T, Jantunen-Backman, K, Korpela, R, Poussa, T, Tuure, T, Kuitunen, M 2004 “Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial”, Allergy,Wiley Online Library, Ref

    Gill, H, Guarner, F 2003 “Probiotics and human health: a clinical perspective”, Postgraduate Medical Journal,BMJ Live, Ref

    Teitelbaum, J, Walker, W 2002 “Nutritional Impact of Pre-and Probiotics as Protective Gastrointestinal Organisms”, Annual Reviews,Pediatric Gastroenterology and Nutrition, Ref

    Gao, J, Li, Y, Wan, Y, Hu, T, Liu, L, Yang, S, Gong, Z, Zeng, Q, Wei, Y, Yang, W, Zeng, Z, He, X, Huang, SH, Cao, H 2019 “A Novel Postbiotic From Lactobacillus rhamnosusGG With a Benedicial Effect on Intestinal Barrier Function”, Department of Microbiology,Frontiersin, Ref

    Cheung, S. G., Goldenthal, A. R., Uhlemann, A.-C., Mann, J. J., Miller, J. M., & Sublette, M. E. (2019, February 11). Systematic Review of Gut Microbiota and Major Depression. Retrieved October 7, 2019, Ref

    Petrosino, J. F. (n.d.). The Human Microbiome Project. Retrieved October 7, 2019, Ref 

    Brookes, J. H., & Hennig. (2000, December 1). Anatomy and physiology of the enteric nervous system. Retrieved October 7, 2019, from https://gut.bmj.com/content/47/suppl_4/iv15. 

    Komaroff, A. L. (n.d.). The gut-brain connection. Retrieved October 7, 2019, Ref

    Sonnenburg, J. (2015, May 1). Gut Feelings–the "Second Brain" in Our Gastrointestinal Systems [Excerpt]. Retrieved October 7, 2019, Ref 

     

    GUT-BRAIN CONNECTION

    Beyond Blue, 2015,”Anxiety”, Austarlian Government, ACT, Ref 

    Hiem, C, Nemeroff, C 1999 “ The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders”, Brain behavior and immunity, Elsevier, Science direct, Volume. 46, Issue.11, p. 1509-1522, Ref 

    Neufeld, K, Kang, N, Bienenstock, J, Foster, J 2011 “Reduced anxiety-like behavior and central neurochemical change in germ-free mice”, Neurogastroenterology and motility, Wiley online library, Ref

    O’Mahony, S, Marches, J, Scully, P, Coding, C, Ceolho, A, Quigley, E, Cryan, J, Dinan, T 2009 “Early life stress alters behavior, immunity, and microbiota in rats: Implications for irritable bowel syndrome and psychiatric illness”, Epigenetic Mechanisms in Psychiatry, Biological Psychiatry, Science Direct, Volume. 65, Issue. 3, p.263-267, Ref

    Perlmutter, D 2015 “Brain Maker”, Little brown and company, Hodder and Stoughton, p. 103-495, 

    Spielberger, C 2010 “State trait anxiety intervention”, Corsini encyclopedia of psychology, Wiley online library

    Stoller-Conrad, J 2015 “Microbes Help Produce Serotonin in Gut” California Institute of Technology, Caltech, Ref

    Breit, S, Kupferberg, A, Rogler, G, Hasler G 2018 “Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatry Inflammatory Disorders”, Frontiers in Psychiatry, US National Library of Medicine National Institutes of Health, Ref

    Gidron, Y, Deschepper R, Couck, M, Thayer, J, Velkeniers, B 2018 “The Vagus Nerve Can predict and Possibly Modulate Non-Communicable Chronic Disease: Introducing a Neuroimmunological Paradigm to Public Health”, Journal of Clinical Medicine, US National Library of Medicine National Institutes of Health, Ref

    Kulkarni, S, Ganz, J, Bayrer, J, Becker, L, Bogunovic, M, Rao, M 2018 “Advances in Enteric Neurobiology: The “Brain” in the Gut in Health and Disease”, JNeurosci, The journal of Neuroscience, Ref

    Carabotti, M, Scirocco, A, Maselli, M, Severi, C 2015 “The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems”, Annals of Gastroenterology, US National Library of Medicine National Institutes of Health, Ref

    Sonnenburg, J 2015 “Gut Feelings- the “Second Brain” in our Gastrointestinal Systems”, Scientific American, Springer Nature, Ref

    Komaroff, A, 2019 “The gut-brain connection”, Healthbeat, Harvard Health Publishing, Harvard Medical School, Ref

    Clapp, M, Aurora, N, Herrera, L, Bhatia, M, Wilen, E, Wakefield, S 2017 “Gut microbiota’s effect on mental health: The gut-brain axis”, Clinics and Practice, US National Library of Medicine National Institutes of Health, Ref

    +BEAUTY RENEWAL PROBIOTIC STRAINS

    1. Immune and clinical impact of Lactobacillus acidophilus on asthma. JG, Wheeler, et al. 1997, Annals of Allergy, Asthma & Immunology. 

    2. Oral administration of Lactobacillus acidophilus alleviates exacerbations in Pseudomonas aeruginosa and Staphylococcus aureus pulmonary infections. Shoaib, A., Xin, L., & Xin, Y. 4, 2019, akistan Journal Of Pharmaceutical Sciences, Vol. 32, pp. 1621–1630. 

    3. The effects of the DDS-1 strain of lactobacillus on symptomatic relief for lactose intolerance - a randomized, double-blind, placebo-controlled, crossover clinical trial. Pakdaman MN, Udani JK, Molina JP, Shahani M. 56, s.l. : BMC, 2016, Nutrition Journal, Vol. 15, pp. 10.1186/s12937-016-0172-y. 

    4. Probiotic Therapy for Irritable Bowel Syndrome. George Aragon, MD, Deborah B. Graham, MD, Marie Borum, MD, EdD, MPH, and David B. Doman, MD, FACP, FACG. 1, NY : Millenium Medical Publishing, Jan 2010, Gastroenterology & Hepatology, Vol. 6, pp. 39-44. 

    5. Effects of Lactobacillus casei Shirota ingestion on common cold infection and herpes virus antibodies in endurance athletes: a placebo-controlled, randomized trial. Gleeson, M., Bishop, N., Struszczak, L., & Bishop, N. C. 8, European Journal of Applied Physiology, Vol. 116, pp. 1555–1563. 

    6. The effect of milk fermented by yogurt cultures plus Lactobacillus casei DN-114001 on the immune response of subjects under academic examination stress. Marcos A, Wärnberg J, Nova E, Gómez S, Alvarez A, Alvarez R, Mateos JA, Cobo JM. 6, s.l. : Epub, Jul 14, 2004, Eur J Nutr., Vol. 43, pp. 381-9. 

    7. Probiotic Lactobacillus casei Zhang reduces pro-inflammatory cytokine production and hepatic inflammation in a rat model of acute liver failure. Wang, Yuzhen, et al. 2, Hohhot : Department of Pharmaceutical Engineering, College of Life Science, Inner Mongolia Agricultural University,, March 2016, European Journal of Nutrition, Vol. 55, pp. 821-831. Ref

    8. Stable Colonization of Orally Administered Lactobacillus casei SY13 Alters the Gut Microbiota. Yue, Yuanchun, et al. Beijing : s.n., February 2020, BioMed Research International, pp. 1-8. 

    9. Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study. Lew, Lee-Ching, et al. 5, Oct 2019, Clinical Nutrition, Vol. 38, pp. 2053-2064. Ref 

    10. Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects. Marco Antonio Moro-García, Rebeca Alonso-Arias, Maria Baltadjieva, Carlos Fernández Benítez, Manuel Amadeo Fernández Barrial, Enrique Díaz Ruisánchez, Ricardo Alonso Santos, Magdalena Álvarez Sánchez, Juan Saavedra Miján & Carlos López-Larrea. May 30, 2012, Official Journal of the American Aging Association, Vol. 35, pp. 1311–1326. 

    11. Evaluation of the Immunomodulatory Activities of the Probiotic Strain Lactobacillus fermentum UCO-979C. Valeria Garcia-Castillo1, 2,3, Ryoya Komatsu3,4, Patricia Clua2, Yuhki Indo3,4, Michihiro Takagi3,4, Susana Salva2, Md. Aminul Islam3,4,5†, Susana Alvarez2, Hideki Takahashi6,7, Apolinaria Garcia-Cancino1*, Haruki Kitazawa3,4* and Julio Villena2,4*. Jun 13, 2019, Front. Immunol. Ref 

    12. Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses. Chiang, B., Sheih, Y., Wang, L. et al. Nov 10, 2000, European Journal of Clinical Nutrition volume , Vol. 54, pp. 849–855. Ref 

    13. Bifidobacterium bifidum PRL2010 modulates the host innate immune response. Applied And Environmental Microbiology. Turroni F, Taverniti V, Ruas-Madiedo P, et al. 2, 2014, Applied And Environmental Microbiology, Vol. 80, pp. 730-740. doi:10.1128/AEM.03313-13.. 

    14. Nature of the antimicrobial activity of Lactobacillus casei, Bifidobacterium bifidum and Bifidobacterium animalis against foodborne pathogenic and spoilage microorganisms. Oliveira CP de, Silva JA da, Siqueira-Júnior JP de. 22, 2015, Natural Product Research, Vol. 29, pp. 2133-2136. 

    15. Randomised Clinical Trial: Bifidobacterium Bifidum MIMBb75 Significantly Alleviates Irritable Bowel Syndrome and Improves Quality of Life--A Double-Blind, Placebo-Controlled Study. S Guglielmetti, D Mora, M Gschwender, K Popp. 10, s.l. : Blackwell Publishing Ltd., 2011, Aliment Pharmacol Ther, Vol. 33, pp. 1123–1132. doi:10.1111/j.1365-2036.2011.04633.x. 

    16. Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement? Palma ML, Zamith-Miranda D, Martins FS, et al. 16, 2015, Applied Microbiology And Biotechnology, Vol. 99, pp. 6563-6570. doi:10.1007/s00253-015-6776-x. 

    17. The potential therapeutic effects of the gut microbiome manipulation by synbiotic containing-Lactobacillus plantarum on neuropsychological performance of diabetic rats. Morshedi, Mohammad, Saghafi-Asl, Maryam and Hosseinifard, Elaheh-Sadat. 1, Jan 10, 2020, Journal of Translational Medicine , Vol. 18, pp. 1-14. Ref 

    18. The Impact of Lactobacillus plantarum on the Gut Microbiota of Mice with DSS-Induced Colitis. Zhang, Fei, et al. Hunan : Hunan Institute of Microbiology, Feb 20, 2019, BioMed Research International, pp. 1-10. 

    +IMMUNITY PROTECT BLEND SCIENTIFIC REFERENCES

    Bone, K. (2003). A Clinical Guide To Blening Liquid Herbs: Herbal Formulations for the Individual Patient. St. Louis, Missouri: Elsevier.

    Carmo, M., Fidelis, M., Pressete, C. G., Marques, M. J., Castro-Gamero, A. M., Myoda, T., . . . Azevedo, L. (2019). Hydroalcoholic Myrciaria dubia (camu-camu) seed extracts prevent chromosome damage and act as antioxidant and cytotoxic agents. Food Research International, 125, 108551. 

    Demling, R. (2009, February). Nutrition, Anabolism, and the Wound Healing Process: An Overview. Eplasty, 9, e9.

    Hapuarachchi, K., Wen, T.-C., Jeewon, R., XL, W., & JC, K. (2016, November). Mycosphere Essays 15. Ganoderma lucidum - Are the beneficial medical properties substantiated? Mycosphere, 7(6), 687– 715.

    Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361–365.

    Heimer, K., Hart, A., Martin, L., & Rubio-Wallace, S. (2009, May). xamining the evidence for the use of vitamin C in the prophylaxis and treatment of the common cold. American Academy of Nurse Practitioners, 21(5), 295–300.

    Inoue, T., Komoda, H., Uchida, T., & & Node, K. (2008). Tropical fruit camu-camu (Myrciaria dubia) has anti-oxidative and anti-inflammatory properties. Journal of Cardiology, 52(2), 127–132.

    Kaneshima, T., Myoda, T., Toeda, K., Fujimori, T., & Nishizawa, M. (2017, August). Antimicrobial constituents of peel and seeds of camu-camu (Myrciaria dubia). Biosci Biotechnol Biochem, 81(8), 1461-1465. 

    Liguori I, R. G.-M. (2018, April). Oxidative stress, aging, and diseases. Clinical interventions in ageing, 13, 757-772.

    MacKay, D., & Miller, A. (2003, Nov 4). Nutritional Support for Wound Healing. Alternative Medicine Review, 8(4), 359–377.

    Pardo-Aldave K, P.-V. M.-T. (2019, Oct 4th). Antimicrobial activity in vitro of Camu-Camu (Myrciaria Dubia) against oral microorganisms: a systematic review. Revista peruana de medicina experimental y salud publica, 36(4), 573–582.

    Porter, R., & Bode, R. (2017). A Review of the Antiviral Properties of Black Elder (Sambucus nigra L.) Products. Phytotherapy research : PTR, 31(4), 533–554.

    Sasazuki, S. S. (2006). Effect of vitamin C on common cold: randomized controlled trial. European Journal of Clinical Nutrition, 60, 9-17.

    Sidor, A., & Gramza-Michałowska, A. (2015, October). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food – a review. Journal of Functional Foods, 18(B), 941-958.

    Whitney, E. e. (2011). Understanding Nutrition (Australian & New Zealand Edition ed.). Melbourne: Cengage Learning Australia.

    Yazawa, K., Suga, K., Honma, A., Shirosaki, M., & Koyama, T. (2011). Anti-inflammatory effects of seeds of the tropical fruit camu-camu (Myrciaria dubia). Journal of nutritional science and vitaminology, 57(1), 104–107.

    Zakay-Rones, Z. e. (n.d.). Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. The Journal of international medical research, 32(2).

    Zheng, D., & Chen, L. (2017, Oct). Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Experimental and Therapeutic Medicine, 14(4), 3273–3278.

    Zhong, Z., Wheeler, M. D., Li, X., Froh, M., Schemmer, P., Yin, M., . . . Lemasters, J. J. (2003, March). L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Current opinion in clinical nutrition and metabolic care, 6(2), 229–240. 

    https://www.healthline.com/nutrition/glycine 

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266414/ 

    https://link.springer.com/article/10.1007/BF01366922   

     

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